Cranial motor neuron input specificity refined by activity

Trends Neurosci. 2024 Nov 27:S0166-2236(24)00223-6. doi: 10.1016/j.tins.2024.11.001. Online ahead of print.

ABSTRACT

A recent study by Kaneko and colleagues provides evidence that developing cranial motor neurons in larval zebrafish refine their input specificity over time, using an activity-dependent mechanism that may depend, in part, on adaptive dendrite extension. These findings illuminate the mechanism by which spatially overlapping motor pools are recruited into distinct motor circuits.

PMID:39609183 | DOI:10.1016/j.tins.2024.11.001